- Medication
- Compounded semaglutide
- Offer
- $119 per month in the current starter view
- Initial cash
- $119 for the one-month starter selection before any location surcharge
- 4-week math
- $119 starter
- Commitment
- The selected plan auto-renews unless canceled at least 24 hours before the period ends; listed medication, membership, and consultation charges are generally nonrefundable.
Cash-pay comparison · September 4th, 2026
Cheapest GLP-1 online without insurance in 2026
The useful answer is not one promotional number. We separate semaglutide from tirzepatide, then compare cash due, supply length, included care, recurring charges, and medication status.
5lower-entry semaglutide offers shown
5lower-entry tirzepatide offers shown
2ingredients kept in separate comparisons
$0paid placement in this report
01
The lowest entry price is not automatically the lowest complete cost.
On September 4th, 2026, Pomegranate showed a $119 one-month compounded semaglutide starter selection before any location surcharge. OLA showed compounded tirzepatide from $129 month to month where its Drug Crafters path was available. Neither figure is universal: state access, pharmacy, formulation, supply, renewal, and clinician approval still control the actual order.
Read the number correctly
Four prices can all be called “monthly.”
A true monthly bill, a prepaid total divided by months, an introductory month, and a clinical membership that excludes medication are different offers. We compare the amount charged first and explain what happens next.
- PRICE TYPE 01
Month to month
One cycle is charged at a time. Check whether it renews automatically and how early cancellation must occur.
- PRICE TYPE 02
Prepaid package
The monthly equivalent may look lower, but the full multi-month total can be due before treatment ships.
- PRICE TYPE 03
Introductory rate
Budget from the published ongoing charge, not just the first discounted cycle.
Lower published entry points
Cash offers without insurance, kept molecule by molecule
These are the five lowest visible entry points in each current dataset, ordered by the first headline amount—not endorsements and not a quality ranking. Open the ingredient ranking for every reviewed offer.
SG
Compounded semaglutide cash comparison
All five paths below require a prescription decision. A low one-month entry can cost more over time than a multi-month package, so the initial payment and commitment belong together.
| Provider | Medication | Published offer | Initial cash | Four-week math | Commitment signal |
|---|---|---|---|---|---|
| Pomegranate Health | Compounded semaglutide | $119 per month in the current starter view | $119 for the one-month starter selection before any location surcharge | $119 starter | The selected plan auto-renews unless canceled at least 24 hours before the period ends; listed medication, membership, and consultation charges are generally nonrefundable. |
| Trillium Meds | Compounded semaglutide | $159 one month, $257 three-month starter, or $357 three-month any-dose | $159, $257, or $357 depending on the selected plan if prescribed | $159 monthly / about $86 starter / $119 any-dose | One- and three-month options are published. Confirm whether the selected plan recurs and its cancellation cutoff before paying. |
| Gimme Care | Compounded semaglutide | $160 one month or $130 per month on a three-month billing cycle | $160 for the one-month path; confirm whether the three-month cycle collects $390 upfront | $160 monthly / $130 on three-month cycle | One- and three-month billing choices auto-renew. The provider says to pause or cancel at least three business days before renewal. |
| Trimi | Compounded semaglutide | $175 monthly, $435 quarterly, $720 for six months, or $1,188 annually | $175 to start month to month; longer plans require their published multi-month total | $175 / $145 / $120 / $99 by term | The $175 plan is month to month. Lower monthly equivalents require prepaid three-, six-, or 12-month commitments. |
| CosmeticRx | Compounded semaglutide | $179 per month with shipping included | $179 for the first monthly cycle if prescribed | $179 | Presented as monthly recurring care. Confirm the renewal and cancellation cutoff before payment. |
- Medication
- Compounded semaglutide
- Offer
- $159 one month, $257 three-month starter, or $357 three-month any-dose
- Initial cash
- $159, $257, or $357 depending on the selected plan if prescribed
- 4-week math
- $159 monthly / about $86 starter / $119 any-dose
- Commitment
- One- and three-month options are published. Confirm whether the selected plan recurs and its cancellation cutoff before paying.
- Medication
- Compounded semaglutide
- Offer
- $160 one month or $130 per month on a three-month billing cycle
- Initial cash
- $160 for the one-month path; confirm whether the three-month cycle collects $390 upfront
- 4-week math
- $160 monthly / $130 on three-month cycle
- Commitment
- One- and three-month billing choices auto-renew. The provider says to pause or cancel at least three business days before renewal.
- Medication
- Compounded semaglutide
- Offer
- $175 monthly, $435 quarterly, $720 for six months, or $1,188 annually
- Initial cash
- $175 to start month to month; longer plans require their published multi-month total
- 4-week math
- $175 / $145 / $120 / $99 by term
- Commitment
- The $175 plan is month to month. Lower monthly equivalents require prepaid three-, six-, or 12-month commitments.
- Medication
- Compounded semaglutide
- Offer
- $179 per month with shipping included
- Initial cash
- $179 for the first monthly cycle if prescribed
- 4-week math
- $179
- Commitment
- Presented as monthly recurring care. Confirm the renewal and cancellation cutoff before payment.
01Pomegranate HealthBest visible starter configurator$119 starter
Fee structure
The pricing app presents a monthly amount and one-, two-, four-, or six-month term choices. Save the final checkout total before enrolling.
What is included
The live app presents a bundled starter selection; final clinical, shipping, and pharmacy details depend on the completed order path.
Pharmacy disclosure
The current view shows semaglutide plus cyanocobalamin (B12) with Empower selected and warns that pharmacy and shipment rules can affect supply.
Before payment
Confirm the complete selected-term charge, shipment cadence, number of vials, renewal date, pharmacy assignment, and any Alaska, Hawaii, or Puerto Rico surcharge.
02Trillium MedsBest pharmacy-level offer matrix$159 monthly / about $86 starter / $119 any-dose
Fee structure
No separate membership fee is advertised. The live offer record presents package totals, and payment is captured after a prescription is issued.
What is included
Clinician review, medication if prescribed, standard shipping, and portal messaging.
Pharmacy disclosure
The live record names the marketing and fulfillment pharmacy, formulation, beyond-use date, carrier, and state coverage for each semaglutide option.
Before payment
Use the live package total rather than a monthly average. Compare formulation, vial count, beyond-use date, state coverage, and renewal status.
03Gimme CareBest simple recurring bundle$160 monthly / $130 on three-month cycle
Fee structure
No separate membership fee. The published rate includes consultation, care, medication if prescribed, supplies, shipping, and support.
What is included
Provider review, unlimited messaging, follow-ups, adjustments, medication if prescribed, supplies, shipping, and portal access.
Pharmacy disclosure
Says compounded GLP-1 prescriptions come from US pharmacies but does not identify the assigned pharmacy or exact formulation on the offer page.
Before payment
Confirm the three-month cash charge, legal pharmacy name, exact formulation, concentration, vial count, total milligrams, and renewal date.
04TrimiBest named-pharmacy flat-dose plans$175 / $145 / $120 / $99 by term
Fee structure
No membership fee. The online visit, medication if prescribed, clinician support, supplies, and expedited shipping are included.
What is included
Licensed-clinician review, medication if prescribed, care-team access, supplies, patient portal, and free expedited shipping.
Pharmacy disclosure
Names VialsRx and GreenwichRx as US 503A sterile compounding pharmacies and states that compounded medication is not FDA-approved.
Before payment
Compare cash due today: the $99 headline is the monthly equivalent of a $1,188 annual charge, not month-to-month billing.
05CosmeticRxMost formulation records exposed$179
Fee structure
Recurring monthly payment. Future shipments can be canceled under the published terms; shipped prescription products cannot be returned.
What is included
Online clinician review, ongoing care, medication if prescribed, and shipping.
Pharmacy disclosure
The official product catalog exposes compounded semaglutide variants, but the patient path still requires confirmation of the assigned formulation and dispensing pharmacy.
Before payment
Get the catalog formulation, concentration, total milligrams, pharmacy, renewal date, and cancellation deadline in writing.
TZ
Compounded tirzepatide cash comparison
Availability changes sharply by pharmacy and state. The lowest path may disappear when a different pharmacy, formulation, or synchronous-visit requirement applies.
| Provider | Medication | Published offer | Cash due | Membership or renewal | Supply |
|---|---|---|---|---|---|
| OLA Health | Compounded tirzepatide | From $129 month to month or $289 for a 12-week starter, where the Drug Crafters path is available | Published options include Drug Crafters at $129 monthly or $289 per 12 weeks; other current pharmacy paths range from $149 to $189 monthly or $349 to $389 for 12 weeks. | No automatic renewal; patients reorder. A state-required synchronous consult adds $25, and an initial medical-screen rejection may be refunded less a $50 consultation fee. | One-month and 12-week starter choices; the available pharmacy, dose, and formulation determine the exact offer |
| Pomegranate Health | Compounded tirzepatide | $149 per month in the current starter view, with one- and two-month choices | The app shows $149 per month but does not make the complete selected-term total and shipment cadence equally prominent before intake. | The selected plan auto-renews unless canceled at least 24 hours before the period ends; medication, membership, and one-time consultation fees are described as nonrefundable. | One- and two-month starter choices are shown in the current pricing app |
| FitnessRx | Compounded tirzepatide | $149 introductory month, then $279 per month for the standard program | $149 at the introductory standard rate, followed by $279 monthly. The separately marketed microdose path starts at $119 and then lists $199 monthly. | Auto-renewing monthly subscription that can be canceled through the dashboard for the end of the current cycle. | Monthly billing and fulfillment |
| Trillium Meds | Compounded tirzepatide | $199 one month or $399 three-month starter through Hyalo/NewLife; other pharmacy totals vary | $199 for the Hyalo/NewLife one-month any-dose plan, $399 for its three-month starter, or $499 for its three-month any-dose plan. Other current paths range from a limited $149 special to $599. | No separate membership fee is advertised. The service is described as subscription-based, but a clear renewal cadence and advance cancellation cutoff are not published in the reviewed legal pages. | One- and three-month packages are listed. The supply-limited $149 Apothecary/NewLife offer is one 72 mg vial with a November 20th, 2026 BUD and does not renew. |
| Gimme Care | Compounded tirzepatide | $199 month to month or $163 per month on a three-month billing cycle | The one-month plan is $199. Multiplying the published $163 monthly rate by the three-month cycle produces $489, but the public page does not clearly state whether that full amount is collected at once. | No separate membership fee is listed, but plans auto-renew. Gimme says to cancel or pause at least three business days before renewal. | One-month and three-month billing choices are published |
- Medication
- Compounded tirzepatide
- Offer
- From $129 month to month or $289 for a 12-week starter, where the Drug Crafters path is available
- Cash due
- Published options include Drug Crafters at $129 monthly or $289 per 12 weeks; other current pharmacy paths range from $149 to $189 monthly or $349 to $389 for 12 weeks.
- Fee model
- No automatic renewal; patients reorder. A state-required synchronous consult adds $25, and an initial medical-screen rejection may be refunded less a $50 consultation fee.
- Supply
- One-month and 12-week starter choices; the available pharmacy, dose, and formulation determine the exact offer
- Medication
- Compounded tirzepatide
- Offer
- $149 per month in the current starter view, with one- and two-month choices
- Cash due
- The app shows $149 per month but does not make the complete selected-term total and shipment cadence equally prominent before intake.
- Fee model
- The selected plan auto-renews unless canceled at least 24 hours before the period ends; medication, membership, and one-time consultation fees are described as nonrefundable.
- Supply
- One- and two-month starter choices are shown in the current pricing app
- Medication
- Compounded tirzepatide
- Offer
- $149 introductory month, then $279 per month for the standard program
- Cash due
- $149 at the introductory standard rate, followed by $279 monthly. The separately marketed microdose path starts at $119 and then lists $199 monthly.
- Fee model
- Auto-renewing monthly subscription that can be canceled through the dashboard for the end of the current cycle.
- Supply
- Monthly billing and fulfillment
- Medication
- Compounded tirzepatide
- Offer
- $199 one month or $399 three-month starter through Hyalo/NewLife; other pharmacy totals vary
- Cash due
- $199 for the Hyalo/NewLife one-month any-dose plan, $399 for its three-month starter, or $499 for its three-month any-dose plan. Other current paths range from a limited $149 special to $599.
- Fee model
- No separate membership fee is advertised. The service is described as subscription-based, but a clear renewal cadence and advance cancellation cutoff are not published in the reviewed legal pages.
- Supply
- One- and three-month packages are listed. The supply-limited $149 Apothecary/NewLife offer is one 72 mg vial with a November 20th, 2026 BUD and does not renew.
- Medication
- Compounded tirzepatide
- Offer
- $199 month to month or $163 per month on a three-month billing cycle
- Cash due
- The one-month plan is $199. Multiplying the published $163 monthly rate by the three-month cycle produces $489, but the public page does not clearly state whether that full amount is collected at once.
- Fee model
- No separate membership fee is listed, but plans auto-renew. Gimme says to cancel or pause at least three business days before renewal.
- Supply
- One-month and three-month billing choices are published
01OLA HealthBest no-auto-renew pharmacy menuFrom $129 month to month or $289 for a 12-week starter, where the Drug Crafters path is available
Medication status
Compounded tirzepatide pharmacy menu. A clinician must determine whether to prescribe.
What is included
Medication if prescribed, ongoing provider access, supplies, educational resources, and shipping; some synchronous consults cost $25
Pharmacy path
The current menu names Drug Crafters, ReviveRx, Mountain Care, White Label/Nova, and New Life/Hyalo, with formulation and state notes. A 503A or 503B label is not proof that the specific prescription is FDA-approved.
Before payment
Enter your state before comparing price. Save the chosen pharmacy, formulation, dose, cash total, consultation fee, vial plan, and refund terms because the lowest path is not available everywhere.
02Pomegranate HealthBest visible starter configurator$149 per month in the current starter view, with one- and two-month choices
Medication status
Compounded tirzepatide plus B6 starter offer. A clinician must determine whether to prescribe.
What is included
The live app presents one bundled monthly figure; verify consultation, medication, shipping, and any pharmacy-coordination fee before paying
Pharmacy path
The current app displays tirzepatide plus B6 with BPI selected, while the terms say pharmacy assignment is not guaranteed and depends on availability and clinical judgment.
Before payment
Save the final checkout summary. Confirm whether $149 is the complete charge, which pharmacy will fill it, how many vials ship, when renewal occurs, and whether location adds shipping.
03FitnessRxBest coaching bundle$149 introductory month, then $279 per month for the standard program
Medication status
Compounded tirzepatide monthly program. A clinician must determine whether to prescribe.
What is included
Medication if prescribed, Body FX app access, behavioral coaching, and provider guidance; shipping terms conflict
Pharmacy path
The comparison page does not identify the pharmacy or 503A/503B route. FDA's Green List concerns certain foreign ingredient manufacturers and import detention—not approval or listing of FitnessRx, its pharmacy, or a finished compounded drug.
Before payment
Budget from the $279 ongoing price, not the $149 intro. Get the pharmacy, formulation, shipping charge, renewal date, and exit timing in writing.
04Trillium MedsBest pharmacy-level comparison$199 one month or $399 three-month starter through Hyalo/NewLife; other pharmacy totals vary
Medication status
Multiple compounded tirzepatide pharmacy plans. A clinician must determine whether to prescribe.
What is included
Clinician review, medication if prescribed, standard shipping, and portal messaging; payment is captured only after a prescription is issued
Pharmacy path
The live matrix names the marketing and fulfillment pharmacy, formulation options, BUD, carrier, and state list. Pharmacy assignment can still change with availability and the prescription.
Before payment
Use the live matrix, not a promotional average. Confirm the chosen pharmacy, fulfillment pharmacy, formulation, number of vials, BUD, total cash charge, and whether the order will recur.
05Gimme CareBest simple three-month price$199 month to month or $163 per month on a three-month billing cycle
Medication status
Compounded tirzepatide program. A clinician must determine whether to prescribe.
What is included
Consultation, medication if prescribed, supplies, shipping, follow-ups, dose adjustments, and portal support
Pharmacy path
Gimme says it uses US pharmacies but does not name the assigned pharmacy or publish the formulation, concentration, or total milligrams on the offer page.
Before payment
Ask for the legal pharmacy name, exact formulation, concentration, vial count, total milligrams, renewal date, and state-specific visit format before the order is released.
Complete-cost method
Calculate the first shipment and the next one.
The lowest responsible comparison uses two totals: what must be paid before the first shipment, and what the same path costs at the next renewal.
Add every required line
Consultation + program fee + medication if prescribed + shipping + supplies + required labs.
Attach time to the total
Record whether the shipment covers four weeks, 8–10 weeks, 11 weeks, or 12 weeks. Do not assume “three months” means three calendar months.
Budget from renewal
Use the ongoing price, dose rule, charge date, and auto-renewal setting—not an introductory or annualized headline.
Compounded and FDA-approved paths are not interchangeable price rows.
The tables above cover provider-described compounded prescriptions. An insurance-supported program may instead charge for clinical care while an FDA-approved medication is paid separately through insurance or cash. Compare those paths in the overall provider ranking.
Common cost questions
Read before treating a headline as your price.
Published prices are evidence of an offer—not a promise of eligibility, a prescription, an assigned pharmacy, or an individual result.
What is the cheapest GLP-1 online without insurance?
There is no responsible single-price answer across unlike medications and supply lengths. In our September 4th, 2026 source check, the lowest published one-month semaglutide starter shown was $119 before any location surcharge, while the lowest published tirzepatide month-to-month entry was $129 where that pharmacy path was available. Eligibility, product status, state, pharmacy, dose, supply, renewal, and separate fees can change the complete cost.
Does the advertised GLP-1 price include medication?
Sometimes. Direct-pay compounded programs often bundle medication if prescribed, while insurance-support programs may quote only the clinical or membership service. Confirm the cash due before the first shipment and every item included in writing.
Can a prepaid plan be cheaper than month-to-month care?
Its monthly equivalent can be lower, but the larger total is generally due on the provider's stated schedule and may carry stricter refund or cancellation terms. Compare cash due today, renewal timing, and supply—not the divided monthly number alone.
Are the compounded offers on this page FDA-approved?
No. The price examples here are provider-described compounded prescription paths. FDA says compounded drugs are not FDA-approved, and a licensed clinician must decide whether any prescription is appropriate.